2. Membrane Transporter/Ion Channel
  3. Na+/H+ Exchanger (NHE)
  4. NHE3-IN-1

NHE3-IN-1 is a sodium/proton exchanger type 3 (NHE-3) inhibitor extracted from patent WO 2011019784 A1.

For research use only. We do not sell to patients.

NHE3-IN-1 Chemical Structure

NHE3-IN-1 Chemical Structure

CAS No. : 632355-68-1

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5 mg USD 50 In-stock
10 mg USD 83 In-stock
25 mg USD 175 In-stock
50 mg USD 280 In-stock
100 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

NHE3-IN-1 is a sodium/proton exchanger type 3 (NHE-3) inhibitor extracted from patent WO 2011019784 A1.

Molecular Weight

263.75

Formula

C12H10ClN3S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC1=CSC(Cl)=C1NC2=NC3=CC=CC=C3N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (473.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7915 mL 18.9573 mL 37.9147 mL
5 mM 0.7583 mL 3.7915 mL 7.5829 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7915 mL 18.9573 mL 37.9147 mL 94.7867 mL
5 mM 0.7583 mL 3.7915 mL 7.5829 mL 18.9573 mL
10 mM 0.3791 mL 1.8957 mL 3.7915 mL 9.4787 mL
15 mM 0.2528 mL 1.2638 mL 2.5276 mL 6.3191 mL
20 mM 0.1896 mL 0.9479 mL 1.8957 mL 4.7393 mL
25 mM 0.1517 mL 0.7583 mL 1.5166 mL 3.7915 mL
30 mM 0.1264 mL 0.6319 mL 1.2638 mL 3.1596 mL
40 mM 0.0948 mL 0.4739 mL 0.9479 mL 2.3697 mL
50 mM 0.0758 mL 0.3791 mL 0.7583 mL 1.8957 mL
60 mM 0.0632 mL 0.3160 mL 0.6319 mL 1.5798 mL
80 mM 0.0474 mL 0.2370 mL 0.4739 mL 1.1848 mL
100 mM 0.0379 mL 0.1896 mL 0.3791 mL 0.9479 mL
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NHE3-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NHE3-IN-1632355-68-1Na+/H+ Exchanger (NHE)Sodium/hydrogen ExchangerSodium-hydrogen ExchangerInhibitorinhibitorinhibit

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