2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. L-Alloisoleucine

L-Alloisoleucine  (Synonyms: (3R)-LS-Isoleucine)

Cat. No.: HY-I1060 Purity: ≥98.0%
SDS
COA
Handling Instructions Technical Support

L-Alloisoleucine is a stereoisomer of L-isoleucine. L-Alloisoleucine can be used in skeletal muscle research.

For research use only. We do not sell to patients.

L-Alloisoleucine Chemical Structure

L-Alloisoleucine Chemical Structure

CAS No. : 1509-34-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid
25 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Alloisoleucine:

L-Alloisoleucine Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE L-Alloisoleucine

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

L-Alloisoleucine is a stereoisomer of L-isoleucine. L-Alloisoleucine can be used in skeletal muscle research[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

L-Alloisoleucine (0.025 mM) increases ILE release by 55% in skeletal muscle but has an inconsistent effect on ILE decarboxylation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Alloisoleucine Related Antibodies
Molecular Weight

131.18

Formula

C6H13NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC[C@@H](C)[C@H](N)C(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (76.23 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.6231 mL 38.1156 mL 76.2311 mL
5 mM 1.5246 mL 7.6231 mL 15.2462 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (190.58 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.7%

SDS (393 KB)

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.6231 mL 38.1156 mL 76.2311 mL 190.5778 mL
5 mM 1.5246 mL 7.6231 mL 15.2462 mL 38.1156 mL
10 mM 0.7623 mL 3.8116 mL 7.6231 mL 19.0578 mL
15 mM 0.5082 mL 2.5410 mL 5.0821 mL 12.7052 mL
20 mM 0.3812 mL 1.9058 mL 3.8116 mL 9.5289 mL
25 mM 0.3049 mL 1.5246 mL 3.0492 mL 7.6231 mL
30 mM 0.2541 mL 1.2705 mL 2.5410 mL 6.3526 mL
40 mM 0.1906 mL 0.9529 mL 1.9058 mL 4.7644 mL
50 mM 0.1525 mL 0.7623 mL 1.5246 mL 3.8116 mL
60 mM 0.1271 mL 0.6353 mL 1.2705 mL 3.1763 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Alloisoleucine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Alloisoleucine1509-34-8(3R)-LS-IsoleucineEndogenous MetabolitemusclestereoisomerInhibitorinhibitorinhibit

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