2. Natural Products
  3. Alkaloids
  4. Aporphine Alkaloids

Aporphine Alkaloids

Aporphine Alkaloids (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0049
    Nuciferine 475-83-2 99.46%
    Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.
    Nuciferine
  • HY-121793
    Roemerine 548-08-3 99.61%
    Roemerine is an alkaloid that has been identified from the leaves of Fibraurea recisa Pierre. Roemerine exhibits antibacterial, anticancer, and antidepressant activities, can reverse the multidrug resistance phenotype in cultured cells, and exerts antibacterial effects by regulating the cAMP signaling pathway. Additionally, Roemerine influences neuronal activity by increasing BDNF protein expression and modulating the serotonergic and glutamatergic systems. Roemerine holds promise for research in the fields of cancer, infections, and neurological diseases.
    Roemerine
  • HY-N2105
    (-)-Dicentrine 28832-07-7 99.80%
    (-)-Dicentrine is an aporphine alkaloid that can be isolated from the stem bark of Talauma arcabucoana. (-)-Dicentrine shows moderate growth inhibition against Staphylococcus aureus and Candida albicans.
    (-)-Dicentrine
  • HY-117616
    Laurotetanine 128-76-7
    Laurotetanine ((+)-Laurotetanine) is an potent and orally active isoquinoline alkaloid and could be extracted from the roots of Litsea cubeba (Lour.) Pers. Laurotetanine exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways.
    Laurotetanine
  • HY-N15227
    (+)-N-Methylhernovine 5550-65-2
    (+)-N-Methylhernovine is an aporphine alkaloid that can be isolated from Hernandia nymphaeifolia. (+)-N-Methylhernovine exhibits slight cytotoxicity in cancer cells.
    (+)-N-Methylhernovine