2. Natural Products
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  4. Simaroubaceae
  5. Brucea antidysenterica J.F.Mill.

Brucea antidysenterica J.F.Mill.

Brucea antidysenterica J.F.Mill. (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0840
    Bruceantin 41451-75-6 99.94%
    Bruceantin(NSC165563) is first isolated from Brucea javanica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.
    Bruceantin
  • HY-N8146
    Bruceantinol 53729-52-5 98.89%
    Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.
    Bruceantinol
  • HY-N7549
    Dehydrobruceantin 53662-98-9
    Dehydrobruceantin has potential antileukemic activity.
    Dehydrobruceantin