2. Anti-infection
  3. Bacterial Antibiotic
  4. Netilmicin sulfate

Netilmicin sulfate  (Synonyms: SCH-20569 sulfate)

Cat. No.: HY-A0086 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

Netilmicin (sulfate) (SCH-20569 (sulfate)) is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin.

For research use only. We do not sell to patients.

Netilmicin sulfate Chemical Structure

Netilmicin sulfate Chemical Structure

CAS No. : 56391-57-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 82 In-stock
Solution
10 mM * 1 mL in Water USD 82 In-stock
Solid
5 mg USD 52 In-stock
10 mg USD 78 In-stock
25 mg USD 147 In-stock
50 mg USD 207 In-stock
100 mg USD 290 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Netilmicin sulfate:

Netilmicin sulfate Related Antibodies

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Netilmicin (sulfate) (SCH-20569 (sulfate)) is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin.

IC50 & Target

Aminoglycoside

 

Clinical Trial
Molecular Weight

720.78

Formula

C21H41N5O7.5/2H2SO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NCC1=CC[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](NCC)[C@H](O[C@@]3([H])OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)([H])O1.[2.5H2SO4]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (138.74 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3874 mL 6.9369 mL 13.8739 mL
5 mM 0.2775 mL 1.3874 mL 2.7748 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (69.37 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.3874 mL 6.9369 mL 13.8739 mL 34.6846 mL
5 mM 0.2775 mL 1.3874 mL 2.7748 mL 6.9369 mL
10 mM 0.1387 mL 0.6937 mL 1.3874 mL 3.4685 mL
15 mM 0.0925 mL 0.4625 mL 0.9249 mL 2.3123 mL
20 mM 0.0694 mL 0.3468 mL 0.6937 mL 1.7342 mL
25 mM 0.0555 mL 0.2775 mL 0.5550 mL 1.3874 mL
30 mM 0.0462 mL 0.2312 mL 0.4625 mL 1.1562 mL
40 mM 0.0347 mL 0.1734 mL 0.3468 mL 0.8671 mL
50 mM 0.0277 mL 0.1387 mL 0.2775 mL 0.6937 mL
60 mM 0.0231 mL 0.1156 mL 0.2312 mL 0.5781 mL
80 mM 0.0173 mL 0.0867 mL 0.1734 mL 0.4336 mL
100 mM 0.0139 mL 0.0694 mL 0.1387 mL 0.3468 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Netilmicin sulfate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Netilmicin56391-57-2SCH-20569SCH20569SCH 20569BacterialAntibioticInhibitorinhibitorinhibit

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