2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. Neurokinin A(4-10)

Neurokinin A (4-10) is a tachykinin NK2 receptor agonist.

For research use only. We do not sell to patients.

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Neurokinin A(4-10) Chemical Structure

Neurokinin A(4-10) Chemical Structure

CAS No. : 97559-35-8

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Neurokinin A(4-10) Related Antibodies

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Description

Neurokinin A (4-10) is a tachykinin NK2 receptor agonist.

IC50 & Target

NK2 receptor[1]
In Vitro

Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Neurokinin A(4-10) Related Antibodies
Molecular Weight

766.91

Formula

C34H54N8O10S
CAS No.
Sequence

Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
Sequence Shortening

DSFVGLM-NH2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Neurokinin A(4-10) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neurokinin A(4-10)97559-35-8Neurokinin ReceptorNK receptorTachykinin receptorInhibitorinhibitorinhibit

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