2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. Neurokinin A(4-10) TFA

Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist.

For research use only. We do not sell to patients.

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Neurokinin A(4-10) TFA Chemical Structure

Neurokinin A(4-10) TFA Chemical Structure

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Other Forms of Neurokinin A(4-10) TFA:

Neurokinin A(4-10) TFA Related Antibodies

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Description

Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist[1].

IC50 & Target

NK2 receptor[1]
In Vitro

Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Neurokinin A(4-10) TFA Related Antibodies
Molecular Weight

880.93

Formula

C36H55F3N8O12S
Appearance

Solid

Color

White to off-white

Sequence

Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
Sequence Shortening

DSFVGLM-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : < 0.1 mg/mL (insoluble)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
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Neurokinin A(4-10) TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neurokinin A(4-10)Neurokinin ReceptorNK receptorTachykinin receptorInhibitorinhibitorinhibit

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