1. Stem Cell/Wnt
  2. Oct3/4
  3. O4I1

O4I1 is as a potent Oct3/4 inducer.

For research use only. We do not sell to patients.

O4I1 Chemical Structure

O4I1 Chemical Structure

CAS No. : 175135-47-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 61 In-stock
Solution
10 mM * 1 mL in DMSO USD 61 In-stock
Solid
5 mg USD 35 In-stock
10 mg USD 55 In-stock
25 mg USD 105 In-stock
50 mg USD 160 In-stock
100 mg USD 280 In-stock
200 mg USD 490 In-stock
500 mg   Get quote  
1 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

O4I1 is as a potent Oct3/4 inducer. Target: Oct3/4 O4I1 enhances Oct3/4 gene expression, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation. O4I1 activates Oct3/4 at the transcriptional and translational levels in diverse human cell lines. O4I1 promotes Oct3/4 expression in untransfected HEK293 cells quantified by qRT-PCR after 72 h of treatment. O4I1 is sufficient to enhance Oct3/4 overexpression 2-fold and 3-fold after 48 and 72 h of treatment, respectively.

Molecular Weight

253.30

Formula

C16H15NO2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

N#CCC1=CC=C(OCC2=CC=C(OC)C=C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 38 mg/mL (150.02 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9479 mL 19.7394 mL 39.4789 mL
5 mM 0.7896 mL 3.9479 mL 7.8958 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9479 mL 19.7394 mL 39.4789 mL 98.6972 mL
5 mM 0.7896 mL 3.9479 mL 7.8958 mL 19.7394 mL
10 mM 0.3948 mL 1.9739 mL 3.9479 mL 9.8697 mL
15 mM 0.2632 mL 1.3160 mL 2.6319 mL 6.5798 mL
20 mM 0.1974 mL 0.9870 mL 1.9739 mL 4.9349 mL
25 mM 0.1579 mL 0.7896 mL 1.5792 mL 3.9479 mL
30 mM 0.1316 mL 0.6580 mL 1.3160 mL 3.2899 mL
40 mM 0.0987 mL 0.4935 mL 0.9870 mL 2.4674 mL
50 mM 0.0790 mL 0.3948 mL 0.7896 mL 1.9739 mL
60 mM 0.0658 mL 0.3290 mL 0.6580 mL 1.6450 mL
80 mM 0.0493 mL 0.2467 mL 0.4935 mL 1.2337 mL
100 mM 0.0395 mL 0.1974 mL 0.3948 mL 0.9870 mL
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O4I1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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