2. Anti-infection
  3. Bacterial
  4. Picloxydine

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

For research use only. We do not sell to patients.

Picloxydine Chemical Structure

Picloxydine Chemical Structure

CAS No. : 5636-92-0

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1 mg USD 260 In-stock
5 mg USD 650 In-stock
10 mg USD 975 In-stock
25 mg USD 1755 In-stock
100 mg USD 2630 In-stock
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Picloxydine Related Antibodies

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Description

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

IC50 & Target

Bacterial[1]
In Vivo

0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms[1]. Picloxydine is also used in eye drops in the topical therapy of trachoma[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

475.38

Formula

C20H24Cl2N10
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N=C(N1CCN(C(NC(NC2=CC=C(Cl)C=C2)=N)=N)CC1)NC(NC3=CC=C(Cl)C=C3)=N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 11.36 mg/mL (23.90 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1036 mL 10.5179 mL 21.0358 mL
5 mM 0.4207 mL 2.1036 mL 4.2072 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1036 mL 10.5179 mL 21.0358 mL 52.5895 mL
5 mM 0.4207 mL 2.1036 mL 4.2072 mL 10.5179 mL
10 mM 0.2104 mL 1.0518 mL 2.1036 mL 5.2590 mL
15 mM 0.1402 mL 0.7012 mL 1.4024 mL 3.5060 mL
20 mM 0.1052 mL 0.5259 mL 1.0518 mL 2.6295 mL
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Picloxydine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Picloxydine5636-92-0BacterialInhibitorinhibitorinhibit

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