2. Metabolic Enzyme/Protease Autophagy Apoptosis
  3. HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis
  4. Pitavastatin-d4

Pitavastatin-d4  (Synonyms: NK-104 d4)

Cat. No.: HY-B0144AS Purity: 99.09%
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Pitavastatin-d4 is deuterium labeled Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor.

For research use only. We do not sell to patients.

Pitavastatin-d<sub>4</sub> Chemical Structure

Pitavastatin-d4 Chemical Structure

CAS No. : 2070009-71-9

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1 mg USD 360 In-stock
5 mg USD 900 In-stock
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Based on 1 publication(s) in Google Scholar

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Pitavastatin-d4 Related Antibodies

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Description

Pitavastatin-d4 is deuterium labeled Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor.

Molecular Weight

425.49

Formula

C25H20D4FNO4
CAS No.
Unlabeled CAS

147511-69-1
Appearance

Solid

Color

Off-white to light yellow

SMILES

FC(C([2H])=C1[2H])=C([2H])C([2H])=C1C2=C(/C=C/[C@@H](O)C[C@@H](O)CC(O)=O)C(C3CC3)=NC4=C2C=CC=C4
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (235.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 100 mg/mL (235.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3502 mL 11.7512 mL 23.5023 mL
5 mM 0.4700 mL 2.3502 mL 4.7005 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.3502 mL 11.7512 mL 23.5023 mL 58.7558 mL
5 mM 0.4700 mL 2.3502 mL 4.7005 mL 11.7512 mL
10 mM 0.2350 mL 1.1751 mL 2.3502 mL 5.8756 mL
15 mM 0.1567 mL 0.7834 mL 1.5668 mL 3.9171 mL
20 mM 0.1175 mL 0.5876 mL 1.1751 mL 2.9378 mL
25 mM 0.0940 mL 0.4700 mL 0.9401 mL 2.3502 mL
30 mM 0.0783 mL 0.3917 mL 0.7834 mL 1.9585 mL
40 mM 0.0588 mL 0.2938 mL 0.5876 mL 1.4689 mL
50 mM 0.0470 mL 0.2350 mL 0.4700 mL 1.1751 mL
60 mM 0.0392 mL 0.1959 mL 0.3917 mL 0.9793 mL
80 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.7344 mL
100 mM 0.0235 mL 0.1175 mL 0.2350 mL 0.5876 mL
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Pitavastatin-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pitavastatin-d42070009-71-9NK-104 d4HMG-CoA Reductase (HMGCR)AutophagyMitophagyApoptosisMitochondrial AutophagyInhibitorinhibitorinhibit

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