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  5. Panax ginseng C. A. Meyer
  6. 20(R)-Protopanaxatriol

20(R)-Protopanaxatriol  (Synonyms: 20(R)-APPT)

Cat. No.: HY-N0798 Purity: 99.70%
SDS COA Handling Instructions

Molarity Calculator

20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh.

For research use only. We do not sell to patients.

20(R)-Protopanaxatriol Chemical Structure

20(R)-Protopanaxatriol Chemical Structure

CAS No. : 1453-93-6

Size Price Stock Quantity
1 mg USD 40 In-stock
5 mg USD 85 In-stock
10 mg USD 135 In-stock
25 mg USD 280 In-stock
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Based on 1 publication(s) in Google Scholar

20(R)-Protopanaxatriol Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh.

Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
58.29 μM
Compound: 8
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
[PMID: 26420067]
HL-60 IC50
28.68 μM
Compound: 8
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 26420067]
In Vitro

20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

20(R)-Protopanaxatriol Related Antibodies
Molecular Weight

476.73

Formula

C30H52O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@@](C[C@H]1O)([H])[C@]([C@]2([H])C3(C)C)(CC[C@@H]3O)C)(C[C@@H]2O)[C@@]([C@@]1([H])[C@@]4([H])[C@](C)(O)CC/C=C(C)\C)(CC4)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 32 mg/mL (67.12 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0976 mL 10.4881 mL 20.9762 mL
5 mM 0.4195 mL 2.0976 mL 4.1952 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.70%

SDS (392 KB)

COA (251 KB) RP-HPLC (212 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0976 mL 10.4881 mL 20.9762 mL 52.4406 mL
5 mM 0.4195 mL 2.0976 mL 4.1952 mL 10.4881 mL
10 mM 0.2098 mL 1.0488 mL 2.0976 mL 5.2441 mL
15 mM 0.1398 mL 0.6992 mL 1.3984 mL 3.4960 mL
20 mM 0.1049 mL 0.5244 mL 1.0488 mL 2.6220 mL
25 mM 0.0839 mL 0.4195 mL 0.8390 mL 2.0976 mL
30 mM 0.0699 mL 0.3496 mL 0.6992 mL 1.7480 mL
40 mM 0.0524 mL 0.2622 mL 0.5244 mL 1.3110 mL
50 mM 0.0420 mL 0.2098 mL 0.4195 mL 1.0488 mL
60 mM 0.0350 mL 0.1748 mL 0.3496 mL 0.8740 mL
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20(R)-Protopanaxatriol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

20(R)-Protopanaxatriol1453-93-620(R)-APPTOthersInhibitorinhibitorinhibit

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