2. Natural Products
  3. Plants Alkaloids Phenols
  4. Aristolochiaceae Indole Alkaloids Monophenols
  5. Aristolochia debilis Sieb. et Zucc.
  6. Sauristolactam

Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation.

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Sauristolactam Chemical Structure

Sauristolactam Chemical Structure

CAS No. : 128533-02-8

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Sauristolactam Related Antibodies

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Description

Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].

Molecular Weight

279.29

Formula

C17H13NO3
CAS No.
SMILES

O=C1N(C2=C3C1=CC(O)=C(C3=C4C(C=CC=C4)=C2)OC)C
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Sauristolactam Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sauristolactam128533-02-8SaurolactamOthersInhibitorinhibitorinhibit

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