2,5-Dihydroxybenzoic acid sodium (Synonyms: Gentisic acid sodium)

Cat. No.: HY-W016704: FAQs
Data Sheet Handling Instructions Technical Support

2,5-Dihydroxybenzoic acid (sodium) (Gentisic acid (sodium)) is a phenolic compound. 2,5-Dihydroxybenzoic acid (sodium) restores mean arterial pressure and reduces blood lactate concentration in animal models of sepsis and septic shock. 2,5-Dihydroxybenzoic acid (sodium) can be used in the study of septic shock related diseases.

For research use only. We do not sell to patients.

2,5-Dihydroxybenzoic acid sodium Chemical Structure

CAS No. : 4955-90-2

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Description

Molecular Weight

176.10

Formula

C₇H₅NaO₄

CAS No.

4955-90-2

SMILES

OC(C=C1)=C(C(O[Na])=O)C=C1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL (283.93 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.6786 mL	28.3930 mL	56.7859 mL
5 mM	1.1357 mL	5.6786 mL	11.3572 mL
10 mM	0.5679 mL	2.8393 mL	5.6786 mL

View the Complete Stock Solution Preparation Table

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mink S, et al. Gentisic acid sodium salt, a phenolic compound, is superior to norepinephrine in reversing cardiovascular collapse, hepatic mitochondrial dysfunction and lactic acidemia in Pseudomonas aeruginosa septic shock in dogs. Intensive Care Med Exp. 2016 Dec;4(1):24. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.6786 mL	28.3930 mL	56.7859 mL	141.9648 mL
	5 mM	1.1357 mL	5.6786 mL	11.3572 mL	28.3930 mL
	10 mM	0.5679 mL	2.8393 mL	5.6786 mL	14.1965 mL
	15 mM	0.3786 mL	1.8929 mL	3.7857 mL	9.4643 mL
	20 mM	0.2839 mL	1.4196 mL	2.8393 mL	7.0982 mL
	25 mM	0.2271 mL	1.1357 mL	2.2714 mL	5.6786 mL
	30 mM	0.1893 mL	0.9464 mL	1.8929 mL	4.7322 mL
	40 mM	0.1420 mL	0.7098 mL	1.4196 mL	3.5491 mL
	50 mM	0.1136 mL	0.5679 mL	1.1357 mL	2.8393 mL
	60 mM	0.0946 mL	0.4732 mL	0.9464 mL	2.3661 mL
	80 mM	0.0710 mL	0.3549 mL	0.7098 mL	1.7746 mL
	100 mM	0.0568 mL	0.2839 mL	0.5679 mL	1.4196 mL

2,5-Dihydroxybenzoic acid sodium Related Classifications

Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,5-Dihydroxybenzoic acid4955-90-2Gentisic acidDrug DerivativeDrug derivativesepsis modelseptic shock modelInhibitorinhibitorinhibit

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2,5-Dihydroxybenzoic acid sodium (Synonyms: Gentisic acid sodium)

2,5-Dihydroxybenzoic acid sodium Related Antibodies

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Biological Activity

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