2. Signaling Pathways
  3. Stem Cell/Wnt
  4. β-catenin
  5. β-catenin Modulator

β-catenin Modulator

β-catenin Modulators (10):

Cat. No. Product Name Effect Purity
  • HY-N0527
    Pentagalloylglucose
    		Modulator 99.77%
    Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities.
  • HY-49597
    Pin1 modulator 1
    		Modulator
    Pin1 modulator 1 (compound IIb-219) is a modulator that specifically targets β-Catenin and inhibits the Wnt pathway. Pin1 modulator 1 can be used in the study of Wnt-mediated related diseases, such as cancer.
  • HY-153682
    β-Catenin modulator-5
    		Modulator
    β-Catenin modulator-5 (compound IIa-84), an oxazole and thiazole compound, is a potent and selective β-Catenin modulator.
  • HY-153680
    β-Catenin modulator-3
    		Modulator
    β-Catenin modulator-3 (compound IIa-112), an oxazole and thiazole compound, is a potent and selective β-Catenin modulator.
  • HY-N0527R
    Pentagalloylglucose (Standard)
    		Modulator
    Pentagalloylglucose (Standard) is the analytical standard of Pentagalloylglucose. This product is intended for research and analytical applications. Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities.
  • HY-163896
    β-Catenin modulator-7
    		Modulator
    β-Catenin modulator-7 (Compound 5) is a modulator for β-catenin. β-Catenin modulator-7 inhibits the expression of β-catenin in HCT-116 cytoplasm and nucleus, suppresses the phosphorylation of GSK 3β. β-Catenin modulator-7 promotes NO release in HCT-116, and inhibits the proliferation of cancer cell HCT-116 with IC50 of 0.6-0.9 μM. β-Catenin modulator-7 can be used in reasearch about colon cancer.
  • HY-153681
    β-Catenin modulator-4
    		Modulator
    β-Catenin modulator-4 (compound IIa-92), an oxazole and thiazole compound, is a potent and selective β-Catenin modulator.
  • HY-153679
    β-Catenin modulator-2
    		Modulator
    β-Catenin modulator-2 (compound IIa-130), an oxazole and thiazole compound, is a potent and selective β-Catenin modulator.
  • HY-153678
    β-Catenin modulator-1
    		Modulator
    β-Catenin modulator-1 (IIa-650) is a β-Catenin modulator useful in cancer research.
  • HY-169126
    β-catenin modulator IIa-661
    		Modulator
    β-catenin modulator IIa-661 is a β-catenin modulator that modulates β-catenin activity and inhibits the activity of the Wnt/wingless (wg) signaling pathway. β-catenin modulator IIa-661 can be utilized in cancer research.