2. Signaling Pathways
  3. Apoptosis
  4. Apoptosis
  5. Apoptosis Agonist

Apoptosis Agonist

Apoptosis Agonists (5):

Cat. No. Product Name Effect Purity
  • HY-N9271
    Grifolin
    		Agonist
    Grifolin is an antineoplastic agent can be isolated from the mushroom Albatrellus confluens and significantly induces apoptosis.
  • HY-157222
    Antitumor agent-125
    		Agonist
    Antitumor agent-125 (compound 17A) is a novel platinum(IV) prodrug. Antitumor agent-125 can activate the mitochondrion-dependent apoptosis pathway. Antitumor agent-125 induces ferroptosis in HCT-116/OXA.
  • HY-161617
    LASSBio-2052
    		Agonist
    LASSBio-2052 is a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC). LASSBio-2052 inhibits HCC cells HepG2 and Hep3B, with IC50 of 18 and 41 μM. LASSBio-2052 arrests the cell cycle at G2/M phase, through downregulation of FOXM1. LASSBio-2052 induces apoptosis in HCC cells.
  • HY-16372
    CP 461
    		Agonist
    CP-461 (OSI-461) is a selective apoptotic antineoplastic drug (SAAND) by engaging tubulin on colchicine site
  • HY-113549
    Erbstatin
    		Agonist
    Erbstatin, a EGFR kinase inhibitor, possesses antineoplastic effect.