2. Signaling Pathways
  3. Apoptosis
  4. Apoptosis
  5. Apoptosis Agonist

Apoptosis Agonist

Apoptosis Agonists (6):

Cat. No. Product Name Effect Purity
  • HY-W011641
    (±)-Naringenin
    		Agonist 98.88%
    (±)-Naringenin is an orally available anti-inflammatory agent that can regulate both acute and chronic inflammation responses, while also showing antioxidant, neuroprotective, liver-protective, and anti-cancer effects. (±)-Naringenin promotes vasodilation in endothelial cells by activating BKCa channels in muscle cells. It also exerts protective effects against experimental colitis by inhibiting Toll-like receptor 4/NF-κB signaling, making it useful in studies related to sepsis, fulminant hepatitis, fibrosis, and cancer research.
  • HY-N9271
    Grifolin
    		Agonist
    Grifolin is an antineoplastic agent can be isolated from the mushroom Albatrellus confluens and significantly induces apoptosis.
  • HY-157222
    Antitumor agent-125
    		Agonist
    Antitumor agent-125 (compound 17A) is a novel platinum(IV) prodrug. Antitumor agent-125 can activate the mitochondrion-dependent apoptosis pathway. Antitumor agent-125 induces ferroptosis in HCT-116/OXA.
  • HY-16372
    CP 461
    		Agonist
    CP-461 (OSI-461) is a selective apoptotic antineoplastic drug (SAAND) by engaging tubulin on colchicine site
  • HY-N9271R
    Grifolin (Standard)
    		Agonist
    Flumethasone pivalate (Standard) is the analytical standard of Flumethasone pivalate. This product is intended for research and analytical applications. Flumethasone pivalate is a glucocorticoid corticosteroid and a corticosteroid ester. Flumetasone pivalate has anti-inflammatory, antipruritic, and vasoconstrictive activities.
  • HY-113549
    Erbstatin
    		Agonist
    Erbstatin, a EGFR kinase inhibitor, possesses antineoplastic effect.