1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N3789
    Dunnianol
    Inhibitor
    Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA).
    Dunnianol
  • HY-B1190S1
    Cefadroxil-d4 trifluoroacetate
    Inhibitor
    Cefadroxil-d4 (trifluoroacetate) is deuterium labeled Cefadroxil.
    Cefadroxil-d<sub>4</sub> trifluoroacetate
  • HY-66011AS3
    Moxifloxacin-d3-1 hydrochloride
    Inhibitor
    Moxifloxacin-d3-1 hydrochloride (BAY 12-8039-d3-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
    Moxifloxacin-d<sub>3</sub>-1 hydrochloride
  • HY-168258
    Antibiofilm agent-13
    Inhibitor
    Antibiofilm agent-13 (compound 14b) is a potent antibacterial agent that displays a broad-spectrum antimicrobial activity. Antibiofilm agent-13 could disintegrate the integrity of bacterial cell membranes by destroying transmembrane potential and enhancing membrane permeability, and causing the generation of intracellular ROS and the leakage of DNA and proteins, ultimately leading to bacterial death. Antibiofilm agent-13 inhibits both Gram-positive bacteria (MIC of 0.5-1 μg/mL) and Gram-negative bacteria (MIC of 1-32 μg/mL).
    Antibiofilm agent-13
  • HY-158380
    UH-NIP-16
    Inhibitor
    UH-NIP-16 exhibits antimicrobial activity against Mycobacterium tuberculosis, with MIC50 of 1.86 and 3.05 μM, for pathogenic mycobacterial strains H37Rv and CDC1551. UH-NIP-16 synergizes with Streptomycin (HY-B1906), Isoniazid (HY-B0329), Ethambutol (HY-B0535) and Bedaquiline (HY-14881), potentiates their anti-tuberculosis activities.
    UH-NIP-16
  • HY-P1259
    PR-39
    Inhibitor
    PR-39, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allosteric proteasome inhibitor. PR-39 reversibly binds to the α7 subunit of the proteasome and blocks degradation of NF-κB inhibitor IκBα by the ubiquitin-proteasome pathway. PR-39 stimulates angiogenesis, inhibits inflammatory responses and significant reduces myocardial infarct size in mice.
    PR-39
  • HY-146650
    LpxC-IN-9
    Inhibitor
    LpxC-IN-9 (compound 19) is a potent LpxC inhibitor. LpxC-IN-9 has antibacterial and hypotensive effects. LpxC-IN-9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    LpxC-IN-9
  • HY-P3116
    Thiocoraline
    Inhibitor
    Thiocoraline is a depsipeptide that can be isolated by marine Micromonospora. Thiocoraline has antitumor activity with IC50s of 0.002, 0.002, 0.01 and 0.002 μg/mL in P388, A549, HT-29 and MEL-28 cells, respectively. Thiocoraline also a strong antimicrobial activity against Gram-positive microorganisms.
    Thiocoraline
  • HY-146119
    Antitubercular agent-24
    Inhibitor
    Antitubercular agent-24 (Compound 1) is an anti-tubercular agent with an extracellular IC50 of 0.83 μM and an intracellular IC50 of 0.17 μM against M. tuberculosis H37Rv.
    Antitubercular agent-24
  • HY-P5630
    Aeschna defensin
    Inhibitor
    Aeschna defensing is an antimicrobial peptide derived from hemolymph of dragonfly aquatic larvae. Aeschna defensing has strong activity against gram-positive bacteria.
    Aeschna defensin
  • HY-N3274
    Methyl isocostate
    Methyl isocostate (compound 24)has antibacterial activity that can be isolated from Globba schomburgkii.
    Methyl isocostate
  • HY-P5697
    Tilapia piscidin 3
    Inhibitor
    Tilapia piscidin 3 is an antimicrobial peptide with antibacterial activity against gram-positive and -negative bacteria (MIC: 2.44, 2.44, 9.78, 19.55, 0.61 μg/mL for V. vulnificus 204, V. alginolyticus, S. agalactiae 819, E. faecalis BCRC 10066, S. agalactiae BCRC 10787). Tilapia piscidin 3 has hemolytic activity in fish red blood cells.
    Tilapia piscidin 3
  • HY-P5829A
    CRAMP (140-173) (mouse) TFA
    Inhibitor
    CRAMP (140-173) (mouse) TFA is a ortholog of human LL-37 antimicrobial peptide. CRAMP (140-173) (mouse) TFA inhibits LPS (HY-D1056)-induced responses, and can not colocalized with TLR3 in BEAS-2B cells.
    CRAMP (140-173) (mouse) TFA
  • HY-121548
    Drimentine A
    Inhibitor
    Drimentine A is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria.nlike Drimentine B and Drimentine C, Drimentine A does not have anticancer activity.
    Drimentine A
  • HY-B1584S
    Captan-d6
    Captan-d6 is the deuterium labeled Captan[1]. Captan is a common agricultural fungicide used to control Botrytis, Fusarium, Fusicoccum, Pythium. Captan enhances denitrifying and total culturable bacteria[2].
    Captan-d<sub>6</sub>
  • HY-147047
    InhA-IN-2
    Inhibitor
    InhA-IN-2 (Compound 23) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 0.31 μM.
    InhA-IN-2
  • HY-153722
    Dodicin
    Inhibitor
    Dodicin is an effective disinfectant with broad antimicrobial activity.
    Dodicin
  • HY-146075
    β-Lactamase-IN-8
    Inhibitor
    β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor. β-Lactamase-IN-8 can be used for researching antibacteria.
    β-Lactamase-IN-8
  • HY-115882
    PptT-IN-1
    PptT-IN-1 (compound 5j) is a potent inhibitor of with phosphopantetheinyl phosphoryl transferase (PptT) an IC50 of 2.8 μM. Phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. PptT-IN-1 has the potential for the research of tuberculosis.
    PptT-IN-1
  • HY-147755
    C16-K-cBB1
    Inhibitor
    C16-K-cBB1 is a potent and selective antimicrobial agent for MRSA (Methicillin resistant Staphylococcus aureus), with a MIC of 1 µg/mL. C16-K-cBB1 has very good selectivity, as it has weak hemolytic activity. C16-K-cBB1 is able to kill MRSA cells in a matter of 120 min at a concentration of 12.5 μg/mL.
    C16-K-cBB1
Cat. No. Product Name / Synonyms Application Reactivity