Moxifloxacin-d₃-1 hydrochloride (Synonyms: BAY 12-8039-d₃-1)

Cat. No.: HY-66011AS3: FAQs
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Moxifloxacin-d₃-1 hydrochloride (BAY 12-8039-d₃-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.

For research use only. We do not sell to patients.

Moxifloxacin-d<sub>3</sub>-1 hydrochloride Chemical Structure

Moxifloxacin-d₃-1 hydrochloride Chemical Structure

CAS No. : 1246816-75-0

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Other Forms of Moxifloxacin-d₃-1 hydrochloride:

Moxifloxacin Hydrochloride In-stock
Moxifloxacin Get quote
Moxifloxacin-d₄ Get quote
Moxifloxacin-d3 Get quote
Moxifloxacin-d₃ hydrochloride Get quote
Moxifloxacin-¹³C,d₃ hydrochloride Get quote
(Rac)-Moxifloxacin Get quote

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Description	Moxifloxacin-d₃-1 hydrochloride (BAY 12-8039-d₃-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia^[1]^[2]^[3].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Moxifloxacin-d₃-1 hydrochloride Related Antibodies
Molecular Weight	440.91
Formula	C₂₁H₂₂D₃ClFN₃O₄
CAS No.	1246816-75-0
Unlabeled CAS	151096-09-2
SMILES	[2H]C([2H])([2H])OC1=C2N(C3CC3)C=C(C(C2=CC(F)=C1N4C[C@@]5([H])[C@@](NCCC5)([H])C4)=O)C(O)=O.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Culley, C.M., et al., Moxifloxacin: clinical efficacy and safety. Am J Health Syst Pharm, 2001. 58(5): p. 379-88. [Content Brief] [2]. Balfour JA, et al. Moxifloxacin: a review of its clinical potential in the management of community-acquired respiratory tract infections. Drugs. 2000 Jan;59(1):115-39. [Content Brief] [3]. Grayo S, et al. Comparison of the in vitro efficacies of moxifloxacin and amoxicillin against Listeria monocytogenes. Antimicrob Agents Chemother. 2008 May;52(5):1697-702. [Content Brief] [4]. Ioannidis O, et al. Effect of moxifloxacin on survival, lipid peroxidation and inflammation in immunosuppressed rats with soft tissue infection caused by Stenotrophomonas maltophilia. Microbiol Immunol. 2014 Feb;58(2):96-102. [Content Brief] [5]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief]

Moxifloxacin-d₃-1 hydrochloride Related Classifications

Infection

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Moxifloxacin-d₃-11246816-75-0BAY 12-8039-d₃-1Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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Moxifloxacin-d3-1 hydrochloride (Synonyms: BAY 12-8039-d3-1)

Other Forms of Moxifloxacin-d3-1 hydrochloride:

Moxifloxacin-d3-1 hydrochloride Related Antibodies

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