2. Signaling Pathways
  3. Anti-infection
  4. Bacterial
  5. Bacterial Modulator

Bacterial Modulator

Bacterial Modulators (10):

Cat. No. Product Name Effect Purity
  • HY-114544A
    N-3-oxo-dodecanoyl-L-homoserine lactone
    		Modulator ≥98.0%
    N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex.Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells.
  • HY-133685
    N-Hexanoyl-L-homoserine lactone
    		Modulator 98.82%
    N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis.
  • HY-W008806
    N-(3-Oxohexanoyl)-L-homoserine lactone
    		Modulator 99.93%
    N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing.
  • HY-N11420
    Coronatine
    		Modulator 98.40%
    Coronatine is a plant growth regulator that mimicks the jasmonic acid-isoleucine conjugate (JA-Ile), targets the jasmonic acid receptor COI1, activates the jasmonic acid signaling pathway, thereby inhibiting salicylic acid (SA)-dependent defense responses. Coronatine antagonizes the stomatal closure, induces plant cell necrosis and chlorosis, interfers with plant hormone balance, thereby promoting pathogen infection.
  • HY-W019806
    Lacto-N-fucopentaose I
    		Modulator 99.92%
    Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development.
  • HY-158730
    N-3-Hydroxybutyryl-L-homoserine lactone
    		Modulator 99.87%
    N-3-Hydroxybutyryl-L-homoserine lactone (3-OH-C4-HSL) is an acyl-homoserine lactone, that can be isolated from Vibrionaceae. N-3-Hydroxybutyryl-L-homoserine lactone is a signaling molecule that is involved in bacterial quorum sensing (QS). N-3-Hydroxybutyryl-L-homoserine lactone senses the density of bacterial population, regulates the cellular process, such as bioluminescence, biofilm formation, and exo-enzyme production.
  • HY-133684
    N-Tetradecanoyl-L-homoserine lactone
    		Modulator 99.63%
    N-Tetradecanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats.
  • HY-E70207
    dam Methyltransferase
    		Modulator
    dam Methyltransferase plays a role in the control of DNA replication in E. coli.
  • HY-134215
    cis-11-Methyl-2-dodecenoic acid
    		Modulator
    cis-11-Methyl-2-dodecenoic acid is a quorum sensing (QS) signal that acts as a diffusion signaling factor (DSF) in extracellular microbial and fungal communication systems. DSF is involved in the regulation of virulence and biofilm formation of a variety of bacterial pathogens.
  • HY-133685S
    N-Hexanoyl-L-homoserine lactone-d3
    		Modulator
    N-Hexanoyl-L-Homoserine lactone-d3 (C6-HSL-d3) is deuterium labeled N-Hexanoyl-L-homoserine lactone. N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats.