2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N8470
    Steffimycin B
    Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine.2 Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s=3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC=5.2 nM), B. cereus (MIC=1.56 μg/mL), and P. falciparum (IC50=2.19 μM).
    Steffimycin B
  • HY-N5142S1
    α-Terpineol-d6
    		Inhibitor
    α-Terpineol-d6 is deuterated labeled Pulegone (HY-N1500). Pulegone, the major chemical constituent of Nepeta catariaessential oil which is an aromatic herb, is one of avian repellents. The molecular target for the repellent action of Pulegone in avian species is nociceptive TRP ankyrin 1 (TRPA1). Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations.
    α-Terpineol-d6
  • HY-161086
    Antibiofilm agent-4
    Antibiofilm agent-4 (compound 4p) is a LasR inhibitor. Antibiofilm agent-4 shows the best antibiofilm and anti-QS properties.
    Antibiofilm agent-4
  • HY-138023
    Leucomycin A4
    		Inhibitor
    Leucomycin A4 is a macrolide antibiotic that can be extracted from S. kitasatoensis. Leucomycin A4 inhibits a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 µg/ml, respectively).
    Leucomycin A4
  • HY-N11722
    Panduratin A
    		Inhibitor
    Panduratin A, a natural chalcone compound, is a PPAR-α/δ activator. Panduratin A induces apoptosis, and promotes cell cycle arrest at G0/G1 phase in multiple hematologic malignant cell lines. Panduratin A has anticancer, antioxidant, anti-inflammatory, antibacterial, and antibiofilm activities.
    Panduratin A
  • HY-126637
    Marasmic acid
    		Inhibitor
    Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
    Marasmic acid
  • HY-N13149
    Tetromycin C1
    		Inhibitor
    Tetromycin C1 is an antibiotic bactericide isolated from Streptomyces sp..
    Tetromycin C1
  • HY-N5173
    Aibellin
    		Inhibitor
    Aibellin, a peptide antibiotic, is a useful and potent modifier of rumen fermentation.
    Aibellin
  • HY-P5545
    Lynronne-1
    		Inhibitor
    Lynronne-1 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 8-32 μg/mL for methicillin-resistant MRSA strains). Lynronne-1 reduces the bacterial load in MRSA infected wound murine model. Lynronne-1 is also effective against P. aeruginosa infection.
    Lynronne-1
  • HY-P5720
    Peptide 5e
    		Inhibitor
    Peptide 5e is an antimicrobial peptide. Peptide 5e inhibits E. coli, S. aureus, and C. albicans with MIC values of 30, 5, 25 μg/mL respectively.
    Peptide 5e
  • HY-N12149
    Axinysone B
    		Inhibitor
    Axinysone B can be isolated from Laurencia similis. Axinysone B has antibacterial activity against Staphylococcus sp..
    Axinysone B
  • HY-N14042
    Arizonin B2
    		Inhibitor
    Arizonin B2 is a microbial metabolite with anti-Gram-positive bacterial activities.
    Arizonin B2
  • HY-163107
    Antimycobacterial agent-7
    		Inhibitor
    Antimycobacterial agent-7 (compound 4) is a 1,2,4-triazole anti-tuberculosis agent (MIC: 2 μg/mL). Antimycobacterial agent-7 inhibits Mtb KatG and causes the accumulation of ROS in Mtb cells. ROS produces oxidative damage, leading to the death of Mtb.
    Antimycobacterial agent-7
  • HY-157142
    Antibacterial agent 165
    		Inhibitor
    Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 165 inhibits methicillin-resistant Staphylococcus aureus (MRSA).
    Antibacterial agent 165
  • HY-W014316R
    5-Bromo-5-nitro-1,3-dioxane (Standard)
    		Inhibitor
    5-Bromo-5-nitro-1,3-dioxane (Standard) is the analytical standard of 5-Bromo-5-nitro-1,3-dioxane. This product is intended for research and analytical applications. 5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol.
    5-Bromo-5-nitro-1,3-dioxane (Standard)
  • HY-W811579
    Bensuldazic acid
    		Inhibitor
    Bensuldazic acid (compound 4f) is a lipophilic 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione (THTT) derivative that can be used as a prodrug model. Bensuldazic acid has antifungal activity.
    Bensuldazic acid
  • HY-B0644R
    Sucralfate (Standard)
    		Inhibitor
    Sucralfate (Standard) is the analytical standard of Sucralfate. This product is intended for research and analytical applications. Sucralfate (Sucrose octasulfate-aluminum complex) is a potent and orally active gastroprotectant with no systemic effects. Sucralfate inhibits peptic activity and binds to negatively charged subepithelial proteins exposed during mucosal injury, forming a viscous layer that protects the vascular bed and proliferative zone. Sucralfate is used for prevention and research of several gastrointestinal diseases in vivo.
    Sucralfate (Standard)
  • HY-169811
    CPW-86-363
    		Inhibitor
    CPW-86-363 is a novel broad-spectrum cephalosporin with antibacterial activity.
    CPW-86-363
  • HY-N14107
    Cinnabarin
    		Inhibitor
    Cinnabarin is an antibiotic which can be extracted from Polystiotus cinnabarinus, P. versicolo and Trametes cinnabarinus. Cinnabarin exhibits antibacterial activity against Gram-positive bacteria as well as antiviral activity, making it a potential candidate for infectious disease research.
    Cinnabarin
  • HY-W653977
    Chlortetracycline-13C,d3 hydrochloride
    		Inhibitor
    Chlortetracycline-13C,d3 hydrochloride (7-Chlorotetracycline-13C,d3 hydrochloride) is the 13C- and deuterium labeled Chlortetracycline hydrochloride (HY-B1327). Chlortetracycline hydrochloride is an orally active, selective antibiotic, that inhibits methanogenic bacteria through inhibition of bacterial protein synthesis. Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, that inhibits binding of aminoacyl-tRNA to ribosomes.
    Chlortetracycline-<sup>13</sup>C,d<sub>3</sub> hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity