2. Signaling Pathways
  3. GPCR/G Protein
    Immunology/Inflammation
  4. CXCR
  5. CXCR7 Isoform
  6. CXCR7 Agonist

CXCR7 Agonist

CXCR7 Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-110318
    VUF11207 fumarate
    		Agonist 98.50%
    VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. VUF11207 fumarate reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation.
  • HY-100677
    VUF11207
    		Agonist
    VUF11207 (Compound 29) is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7.