2. Signaling Pathways
  3. GPCR/G Protein
  4. CaSR
  5. CaSR Inhibitor

CaSR Inhibitor

CaSR Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-11095
    NPS 2390
    		Inhibitor 98.83%
    NPS 2390 is a noncompetitive antagonist of mGluR1 and mGluR5. NPS 2390 is also a potent CaSR (calcium-sensing receptor) inhibitor.
  • HY-103320A
    Calhex 231 hydrochloride
    		Inhibitor 99.81%
    Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC50 = 0.39 μM) increases in [3H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca2+-sensing receptor. Calhex 231 hydrochloride can be used in the study of traumatic hemorrhagic shock (THS) and diabetic cardiomyopathy (DCM).