2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Dopamine Receptor
  5. Dopamine Receptor Isoform

Dopamine Receptor

 

Dopamine Receptor Related Products (490):

Cat. No. Product Name Effect Purity
  • HY-B1573A
    (±)-Butaclamol hydrochloride
    		Antagonist
    (±)-Butaclamol hydrochloride (AY-23,028) is the antagonist for adrenergic receptor and dopamine receptor. (±)-Butaclamol hydrochloride antagonizes amphetamine or Apomorphine (HY-12723)-induced stereotyped behaviors and emesis, inhibits discriminative avoidance behavior, and induces catalepsy in rats models.
  • HY-112015
    Deschlorohaloperidol
    Deschlorohaloperidol (compound 8h) is an analogue of Haloperidol (HY-14538). Haloperidol is a dopamine D2 receptor (D2R) antagonist for schizophrenia.
  • HY-B0031S2
    Quetiapine-d8 fumarate
    		Antagonist
    Quetiapine-d8 (fumarate) is the deuterium labeled Quetiapine. Quetiapine is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine has moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects[1][2].
  • HY-B0411S
    Domperidone-d6
    		Inhibitor
    Domperidone-d6 is the deuterium labeled Domperidone. Domperidone (R33812) is a selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine[1][2].
  • HY-10847
    SB-277011
    		Antagonist
    SB-277011 is a potent and delective dopamine D3 receptor antagonist (pKi values are 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively); brain penetrant.
  • HY-A0040
    Talipexole
    		Agonist
    Talipexole (B-HT920) is a dopamine agonist that has been proposed as an antiparkinsonian agent.
  • HY-19845A
    Ordopidine hydrochloride
    		Modulator
    Ordopidine hydrochloride is a modulator of dopamine receptor extracted from patent WO/2005/121087A1, compound example 2; exhibits an ED50 of 68 μmol/kg on increase of DOPAC in the rat striatum.
  • HY-U00400
    PF-592379
    		Agonist
    PF-592379 is a potent dopamine D3 receptor agonist with an EC50 of 21 nM.
  • HY-U00415
    Benzamide Derivative 1
    		Antagonist
    Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 may be useful in treatment of gastrointestinal disorders.
  • HY-U00227
    U91356
    		Agonist
    U91356 is a dopamine receptor agonist.