2. Signaling Pathways
  3. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  4. EGFR
  5. EGFR Isoform
  6. EGFR Modulator

EGFR Modulator

EGFR Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-125168
    EGA
    		Modulator ≥99.0%
    EGA is a selective inhibitor of endosomol trafficking pathways exploited by multiple toxins and virus[1].
  • HY-402309
    IGF-1R modulator 1
    		Modulator
    IGF-1R modulator 1 (Example 5) is an IGF-1R modulator, with EC50s of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB). IGF-1R modulator 1 can be used for research of diseases characterised by impaired signalling of neurotrophins and/or other trophic factors, such as Alzheimer's disease.