2. Signaling Pathways
  3. GPCR/G Protein
  4. GPR84
  5. GPR84 Agonist

GPR84 Agonist

GPR84 Agonists (9):

Cat. No. Product Name Effect Purity
  • HY-12764
    6-OAU
    		Agonist 99.91%
    6-OAU (GTPL5846) (6-n-octylaminouracil) is an GPR84 (G protein-coupled receptor 84) agonist, with an EC50 value of 105 nM. 6-OAU works as a chemoattractant to both PMNs and macrophages, and amplifies the proinflammatory cytokine IL-8, shows proinflammatory function. 6-OAU also displays anti-bacterial function.
  • HY-124571
    ZQ-16
    		Agonist 99.88%
    ZQ-16 is a potent and selective GPR84 agonist with an EC50 value of 0.213 μM. ZQ-16 has no activity on the other free fatty acid receptors (FFARs), including GPR40, GPR41, GPR119 and GPR120.
  • HY-12764R
    6-OAU (Standard)
    		Agonist
    Prochloraz manganese (Standard) is the analytical standard of Prochloraz manganese. This product is intended for research and analytical applications. Prochloraz manganese is an antifungal agent, and is used in agricultural industries.
  • HY-163350
    TUG-2208
    		Agonist 98.09%
    TUG-2208 (compound 42a) is a GPR84 agonist (pEC50=8.98) with low lipophilicity and good solubility, in vitro permeability and microsomal stability.
  • HY-161106
    OX04528
    		Agonist 99.71%
    OX04528 (compound 68) is a potent, G-protein biased, and orally active GPR84 agonist. OX04528 no cytotoxicity. OX04528 inhibits cAMP production with an EC50 value of 0.00598 nM.
  • HY-126346
    DL-175
    		Agonist ≥99.0%
    DL-175 (compound 13) is a selective GPR84 agonist with biased agonistic activity. DL-175 can selectively activate functional responses in immune cells and induce enhanced chemotaxis and phagocytosis of human bone marrow cells. DL-175 is a potential chemical probe.
  • HY-171115
    Pyrone-211
    		Agonist 99.32%
    Pyrone-211 is a potent GPR84 agonist and AKR1C3 inhibitor. Pyrone-211 participates in an expanded polyamine pathway.
  • HY-W182770
    GPR84 agonist-1
    		Agonist
    GPR84 agonist-1 (Compound LY214-5) is a GPR84 agonist, with an EC50 of 2.479 μM. GPR84 agonist-1 can be used for the research of septicemia.
  • HY-161107
    OX04529
    		Agonist
    OX04529 (compound 69) is a potent, selective and orally active agonist of GPR84. OX04529 inhibits FSK-induced cAMP production with an EC50 of 0.0185 nM. OX04529 displayed excellent potency, high G-protein signaling bias.