2. GPCR/G Protein
  3. GPR84
  4. OX04528

OX04528 (compound 68) is a potent, G-protein biased, and orally active GPR84 agonist. OX04528 no cytotoxicity. OX04528 inhibits cAMP production with an EC50 value of 0.00598 nM.

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OX04528 Chemical Structure

OX04528 Chemical Structure

CAS No. : 3028055-45-7

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1 mg USD 186 In-stock
5 mg USD 466 In-stock
10 mg USD 700 In-stock
25 mg USD 1400 In-stock
50 mg USD 2100 In-stock
100 mg USD 3150 In-stock
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Based on 1 publication(s) in Google Scholar

OX04528 Related Antibodies

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Description

OX04528 (compound 68) is a potent, G-protein biased, and orally active GPR84 agonist. OX04528 no cytotoxicity. OX04528 inhibits cAMP production with an EC50 value of 0.00598 nM[1].

Molecular Weight

365.27

Formula

C16H13F6NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[O-][N+]1=CC(CCCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=CC(O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (273.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7377 mL 13.6885 mL 27.3770 mL
5 mM 0.5475 mL 2.7377 mL 5.4754 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7377 mL 13.6885 mL 27.3770 mL 68.4425 mL
5 mM 0.5475 mL 2.7377 mL 5.4754 mL 13.6885 mL
10 mM 0.2738 mL 1.3689 mL 2.7377 mL 6.8443 mL
15 mM 0.1825 mL 0.9126 mL 1.8251 mL 4.5628 mL
20 mM 0.1369 mL 0.6844 mL 1.3689 mL 3.4221 mL
25 mM 0.1095 mL 0.5475 mL 1.0951 mL 2.7377 mL
30 mM 0.0913 mL 0.4563 mL 0.9126 mL 2.2814 mL
40 mM 0.0684 mL 0.3422 mL 0.6844 mL 1.7111 mL
50 mM 0.0548 mL 0.2738 mL 0.5475 mL 1.3689 mL
60 mM 0.0456 mL 0.2281 mL 0.4563 mL 1.1407 mL
80 mM 0.0342 mL 0.1711 mL 0.3422 mL 0.8555 mL
100 mM 0.0274 mL 0.1369 mL 0.2738 mL 0.6844 mL
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OX04528 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OX045283028055-45-7OX 04528OX-04528GPR84G protein coupled receptor 84Orally BioavailableInhibitorinhibitorinhibit

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