2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  4. HSP
  5. HSPA5 Isoform
  6. HSPA5 Inhibitor

HSPA5 Inhibitor

HSPA5 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-125974
    HM03
    		Inhibitor 99.34%
    HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity.
  • HY-152153
    GRP78-IN-3
    		Inhibitor 99.98%
    GRP78-IN-3 (Compound 8) is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 μM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of 4.3 μM) and >20-fold selective for HspA5 compared to HspA2 (IC50 of 13.9 μM).