2. Signaling Pathways
  3. GPCR/G Protein
    Immunology/Inflammation
    Neuronal Signaling
  4. Histamine Receptor
  5. H2 Receptor Isoform
  6. H2 Receptor Antagonist

H2 Receptor Antagonist

H2 Receptor Antagonists (29):

Cat. No. Product Name Effect Purity
  • HY-106078
    Oxmetidine
    		Antagonist
    Oxmetidine (SKF 92994) is an orally active H2-receptor antagonist, and is an anti-ulcer agent.
  • HY-10121B
    Asenapine citrate
    		Antagonist
    Asenapine citrate, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine citrate can be used in the research of schizophrenia and bipolar disorder.
  • HY-122148
    DA 4626
    		Antagonist
    DA 4626 is a competitive H2-histamine receptor antagonist. DA 4626 inhibits adenylate cyclase activity with a KB value of 40 nM.
  • HY-19048
    CP-66948
    		Antagonist
    CP-66948 is a histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties.
  • HY-B0305
    Roxatidine acetate
    		Antagonist
    Roxatidine acetate is a potent, selective, competitive and orally active histamine H2-receptor antagonist. Roxatidine acetate has antisecretory potency against gastric acid secretion. Roxatidine acetate can also suppress inflammatory responses and can be used for gastric and duodenal ulcers research. Roxatidine acetate has antitumor activity.
  • HY-121450
    Lavoltidine
    		Antagonist
    Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia.
  • HY-B0377S
    Famotidine-13C,d3
    		Antagonist
    Famotidine-13C,d3 is the 13C- and deuterium labeled Famotidine. Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
  • HY-100191
    BMY-25271
    		Antagonist
    BMY-25271 is a histamine H2 receptor antagonist.
  • HY-B0281AS
    Ranitidine-d6 hydrochloride
    		Antagonist
    Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride (HY-B0281A). Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine hydrochloride antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride inhibits breast tumor development and spread in mice.