2. Signaling Pathways
  3. Cytoskeleton
  4. Integrin
  5. α9β1 Isoform
  6. α9β1 Inhibitor

α9β1 Inhibitor

α9β1 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-107589
    BIO5192
    		Inhibitor 99.96%
    BIO5192 is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels.
  • HY-107589A
    BIO5192 hydrate
    		Inhibitor 99.96%
    BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels.
  • HY-129453
    BOP sodium
    		Inhibitor 99.11%
    BOP sodium is a potent and selective dual α9β1/α4β1 integrin inhibitor with Kd values in the picomolar range. BOP sodium shows the rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. BOP sodium has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins.