2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W007319
    Phenylpropiolic acid
    		99.29%
    Phenylpropiolic acid is an endogenous metabolite. Phenylpropiolic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Phenylpropiolic acid
  • HY-N0390S4
    L-Glutamine-5-13C
    		≥98.0%
    L-Glutamine-5-13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine-5-<sup>13</sup>C
  • HY-B1779R
    Sucrose (Standard)
    Sucrose (Standard) is the analytical standard of Sucrose. This product is intended for research and analytical applications. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose?can be applied in some animal models, including metabolic disease, obesity,?diet on preference,?and diabetes, et al.
    Sucrose (Standard)
  • HY-W015343
    3-Methoxyphenylacetic acid
    		99.57%
    3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot.
    3-Methoxyphenylacetic acid
  • HY-W008385S
    H-HoArg-OH-d4
    H-HoArg-OH-d4 is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.
    H-HoArg-OH-d<sub>4</sub>
  • HY-I0400S3
    N-Acetylneuraminic acid-13C-3
    N-Acetylneuraminic acid-13C-3 is the 13C labeled N-Acetylneuraminic acid.
    N-Acetylneuraminic acid-<sup>13</sup>C-3
  • HY-E70264
    16:0 Coenzyme A triammonium
    		≥99.0%
    16:0 Coenzyme A triammonium is palmitoyl-CoA, which can serve as a reaction substrate to transfer the palmitoyl group to the free thiol group of the target protein through palmitoylation catalyzed by protein acyl transferases (PATs).
    16:0 Coenzyme A triammonium
  • HY-121385
    Hydroxy bosentan
    		≥98.0%
    Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities.
    Hydroxy bosentan
  • HY-126359
    1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine
    1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can be chosen as a model used to investigate the volatile compounds from oxidised phosphatidylcholine molecular species. This method is applied to a real food sample, i.e. soy lecithin.
    1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine
  • HY-118103S
    Coprostanol-d5
    		99.30%
    Coprostanol-d5 is the deuterium labeled Coprostanol[1].
    Coprostanol-d<sub>5</sub>
  • HY-N12706
    Heilaohuguosu G
    		≥98.0%
    Heilaohuguosu G (compound 7) is a cyclolignan with hepatoprotective activity. Heilaohuguosu G against APAP toxicity with cell survival rates at 10 μM of 45.7% in HepG-2 cells.
    Heilaohuguosu G
  • HY-121765
    Dacisteine
    		99.40%
    Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation.
    Dacisteine
  • HY-N8063
    γ-Glutamylornithine
    		≥98.0%
    γ-Glutamylornithine is the urine excreta of patients with HHH syndrome (hyperuricemia, hyperaminemia, and hypercitrullinuria) and rotary atrophy associated with hyperuricemia. Increased levels of endogenous ornithine increase levels of γ-Glutamylornithine in the urine.
    γ-Glutamylornithine
  • HY-B1673
    Pharmatose DCL 14
    		99.87%
    Pharmatose DCL 14 is an endogenous metabolite.
    Pharmatose DCL 14
  • HY-P2746
    Carboxypeptidase B, Porcine pancreas
    Carboxypeptidase B, Porcine pancreas (EC 3.4.2.2) is a peptide exonuclease that can specifically degrade peptide chains. Carboxypeptidase B is progressively degraded from the C-terminal to release free amino acids. Carboxypeptidase B hydrolyzes only peptide bonds with basic amino acids (such as arginine and lysine) as C-terminal residues.
    Carboxypeptidase B, Porcine pancreas
  • HY-W010476
    2,3,5-Trimethylpyrazine
    		99.92%
    2,3,5-Trimethylpyrazine is an endogenous metabolite.
    2,3,5-Trimethylpyrazine
  • HY-P2992
    Inorganic pyrophosphatase, Saccharomyces cerevisiae
    Inorganic pyrophosphatase, Saccharomyces cerevisiae (PPase) converts pyrophosphate (PPi) to phosphate. Inorganic pyrophosphatase is an essential component of in vitro transcription reactions for RNA preparation, is often used in biochemical studies. Inorganic pyrophosphatase is critical for driving cellular processes such as nucleic acid and protein synthesis.
    Inorganic pyrophosphatase, Saccharomyces cerevisiae
  • HY-B1538A
    Bamethan hemisulfate
    		≥98.0%
    Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.
    Bamethan hemisulfate
  • HY-113227R
    Oxoadipic acid (Standard)
    Oxoadipic acid (Standard) is the analytical standard of Oxoadipic acid. This product is intended for research and analytical applications. Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.
    Oxoadipic acid (Standard)
  • HY-113420
    11-Dehydro-thromboxane B2
    		≥98.0%
    11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis.
    11-Dehydro-thromboxane B2
Cat. No. Product Name / Synonyms Application Reactivity