Endogenous Metabolite

Related Products

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite Related Products (7425)
Antibodies (477)

By Effects:	Controls (3) Inhibitors (32) Agonist (1) Antagonist (1) Activators (2) Modulators (8) Chemicals (2) Inducers (6)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0166S8

L-Ascorbic acid-¹³C₆-1		99.15%
L-Ascorbic acid-¹³C₆-1 (L-Ascorbate-1; Vitamin C-¹³C₆-1) is a ¹³C labeled L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells.

HY-W008253S2

5-Hydroxyindole-3-acetic acid-d₅
5-Hydroxyindole-3-acetic acid-d₅ is the deuterium labeled 5-Hydroxyindole-3-acetic acid (HY-W008253). 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.

HY-B1654S

Flavin adenine dinucleotide-¹³C₅ ammonium
Flavin adenine dinucleotide-¹³C5 (FAD-¹³C5) ammonium is ¹³C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-112169

10-Formyltetrahydrofolic acid
10-Formyltetrahydrofolic acid is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines.

HY-127061

Palmitoleoyl ethanolamide		99.77%
Palmitoleoyl ethanolamide (POEA) is an endogenous fatty amide with biological activity.

HY-N15156

Thiotaurine
Thiotaurine is the metabolite of Cystine. Thiotaurine is a sulfur donor, which may probably modulates the activity of GAPDH, followed by the pparticipation in neutrophil activation and leukocytes energy metabolism. Thiotaurine is a potential anti-inflammatory agent and immunomodulator.

HY-W008638R

2'-Deoxyinosine (Standard)
2'-Deoxyinosine (Standard) is the analytical standard of 2'-Deoxyinosine (HY-W008638). This product is intended for research and analytical applications. 2’-deoxyadenosine inhibits the growth of human colon-carcinoma cell lines and is found to be associated with purine nucleoside phosphorylase (PNP) deficiency.

HY-128851R

Coenzyme A (Standard)

HY-168761

N-Cholyl-L-alanine		99.2%
N-Cholyl-L-alanine is a bile acid amidate, which is found in human fecal samples.

HY-125140

ω-3 Arachidonic acid
ω-3 Arachidonic acid is a poly fatty acid that is essential for growth and development in infants. ω-3 Arachidonic acid inhibits arachidenol-CoA synthetase with K_i values of 14 µM. It also inhibited arachidenol-CoA synthetase of calf brain extract with IC₅₀ values of about 5 µM.

HY-126720

N-Lignoceroyl Taurine		≥99.0%
N-Lignoceroyl Taurine is an arachidonoyl amino acid and taurine conjugate with a fatty acid that can be isolated from bovine brain. N-Lignoceroyl Taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of the brain and spinal cord of wild-type and fatty acid amide hydrolase (FAAH) knockout mice. N-Lignoceroyl Taurine levels were 23-26-fold higher in FAAH^-/- mice compared to wild-type mice, suggesting that FAAH utilizes N-Lignoceroyl Taurine as a substrate. However, in vitro experiments with purified FAAH showed that N-Lignoceroyl Taurine was hydrolyzed 2,000-fold slower in FAAH compared to oleoylethanolamide. N-Acyl Taurines with polyunsaturated acyl chains can activate members of the transient receptor potential (TRP) calcium channel family, including TRPV1 and TRPV4.

HY-B2156R

Menaquinone-4 (Standard)
Menaquinone-4 (Standard) is the analytical standard of Menaquinone-4. This product is intended for research and analytical applications. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-W074081

(CAAC-Cy)Rh(COD)Cl
(CAAC-Cy)Rh(COD)Cl is a rhodium-based catalyst with significant hydrogenation activity. (CAAC-Cy)Rh(COD)Cl is widely used in organic synthesis to catalyze different types of reactions. (CAAC-Cy)Rh(COD)Cl is highly efficient in promoting hydrogenation reactions. (CAAC-Cy)Rh(COD)Cl can effectively catalyze the conversion of certain unsaturated compounds.

HY-90006R

5-Fluorouracil (Standard)
5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV.

HY-W601362

N-Acetyl-D-galactosamine-6-phosphate disodium		≥98.0%
N-Acetyl-D-galactosamine-6-phosphate disodium is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate disodium can be hydrolyze by NagA.

HY-W011176

(S)-3-Hydroxypropane-1,2-diyl dioctanoate		98.42%
(S)-3-Hydroxypropane-1,2-diyl dioctanoate (1,2-Dioctanoyl-sn-glycerol) is a cell-permeable analog of the PKC-activating second messenger DAG. (S)-3-Hydroxypropane-1,2-diyl dioctanoate induces acrosome reaction in human sperm.

HY-B0964R

Riboflavin phosphate (sodium) (Standard)
Riboflavin phosphate (sodium) (Standard) is the analytical standard of Riboflavin phosphate (sodium). This product is intended for research and analytical applications. Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism. Riboflavine phosphate sodium is a very effective NAD+-recycling agent.

HY-113031S1

16α-Hydroxydehydroepiandrosterone-d₅
16α-Hydroxydehydroepiandrosterone-d₅ (16α-Hydroxy-DHEA-d₅) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone (HY-113031).

HY-N0538R

Xylitol (Standard)
Xylitol (Standard) is the analytical standard of Xylitol. This product is intended for research and analytical applications. Xylitol can be classified as polyols and sugar alcohols.

HY-N7032S1

Uridine 5′-diphosphoglucose-¹³C₆ disodium		98.35%
Uridine 5′-diphosphoglucose-¹³C₆ (disodium) is the ¹³C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].

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Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite Related Products (7425)

Antibodies (477)

Endogenous Metabolite Related Products (7425):