2. Signaling Pathways
  3. Epigenetics
  4. MicroRNA
  5. MicroRNA Antagonist

MicroRNA Antagonist

MicroRNA Antagonists (3):

Cat. No. Product Name Effect Purity
  • HY-112659
    Lin28-let-7 antagonist 1
    		Antagonist 99.68%
    Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells.
  • HY-100692
    Lin28-let-7a antagonist 1
    		Antagonist 99.48%
    Lin28-let-7a antagonist 1 shows a clear antagonistic effect against the Lin28-let-7a interaction with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction.
  • HY-132600
    RG-101
    		Antagonist
    RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication.