2. Signaling Pathways
  3. Others
  4. Others
  5. Others Activator

Others Activator

Others Activators (38):

Cat. No. Product Name Effect Purity
  • HY-123962
    G6PD activator AG1
    		Activator 99.54%
    G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) activator with an EC50 of 3 µΜ. G6PD activator AG1 reduces hemolysis of human erythrocytes.
  • HY-115768
    Compound 48/80
    		Activator 99.98%
    Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways.
  • HY-13610A
    N1,N11-Diethylnorspermine tetrahydrochloride
    		Activator ≥98.0%
    N1,N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity.
  • HY-B1058
    Benfluorex hydrochloride
    		Activator 99.96%
    Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator.
  • HY-147313
    TH10785
    		Activator 99.93%
    TH10785 is a DNA glycosylase 1 (OGG1) activator, TH10785 can interact with the phenylalanine-319 and glycine-42 amino acids of OGG1 and increase the enzyme activity, generates β, δ-lyase enzymatic function. TH10785 can control the catalytic activity mediated by a nitrogen base within its molecular structure. TH10785 can be used for the research of various diseases and aging connected with DNA oxidative lesions.
  • HY-B0711
    Carglumic Acid
    		Activator 99.84%
    Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
  • HY-108036
    Pro-xylane
    		Activator ≥98.0%
    Pro-xylane (Hydroxypropyl tetrahydropyrantriol) is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. Pro-xylane is the first example of 'Green' chemical used in cosmetic.
  • HY-109121
    Reldesemtiv
    		Activator 99.72%
    Reldesemtiv (CK-2127107) is a selective, orally active and next-generation fast skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates fast skeletal myofibrils with an EC50 of 3.4 μM. Reldesemtiv increases exercise performance in a heart failure model.
  • HY-19694
    BRD7552
    		Activator 99.32%
    BRD7552, a potent PDX1 transcription factor inducer, upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases insulin expression. PDX1 is a key transcription factor involved in pancreas development and β cell function.
  • HY-112440
    HZX-02-059
    		Activator 99.40%
    HZX-02-059 is a potent methuosis inducer. Anticancer activity.
  • HY-134334
    C/EBPα inducer 1
    		Activator 99.85%
    C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation.
  • HY-N0818
    Chikusetsusaponin Iva
    		Activator 98.95%
    Chikusetsusaponin Iva is the main active component of triterpenoid saponins, acts as an activator of protein kinases, and has a resistance effect against thrombosis and some metabolic diseases.
  • HY-147292
    Nelutroctiv
    		Activator 99.38%
    Nelutroctiv (CK-136) is a potent cardiac troponin activator.
  • HY-120872
    AJS1669 free acid
    		Activator 99.15%
    AJS1669 free acid is a potent and orally available glycogen synthase (GS) activator. AJS1669 improves glucose metabolism and reduces body fat mass in mice[1].
  • HY-109194
    Udonitrectag
    		Activator 98.46%
    Udonitrectag (REC 0559), a low molecular weight compound that mimics NGF, aims to address the issue of NGF stability.
  • HY-155539
    Cisd2 agonist 2
    		Activator 99.17%
    Cisd2 agonist 2 (compound 6) is an orally active Cisd2 activator (EC50=191 nM), while the Cisd2 levels is correlated with nonalcoholic fatty liver disease (NAFLD). Cisd2 agonist 2 has no significant toxicity in vivo in Cisd2hKO-het mice (heterozygous hepatocyte-specific Cisd2 knockout).
  • HY-16232
    GLUFOSFAMIDE
    		Activator ≥98.0%
    Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.
  • HY-162345
    CK-963
    		Activator 99.67%
    CK-963 is an activator for cardiac troponin (cTnC) with Ki of 11.5 μM. CK-963 exhibits activity in enhancing cardiac contractility in Sprague-Dawley rats.
  • HY-119994
    DFPM
    		Activator 99.4%
    DFPM activates plant resistance protein signaling in roots, and triggers root growth arrest. DFPM decreases root cell viability in accession Col-0. DFPM is light sensitive in aqueous solutions. DFPM becomes bioactive during light and oxygen-dependent modification.
  • HY-P6022
    G4RGDSP, integrin-binding peptide
    		Activator 99.61%
    G4RGDSP, Integrin-binding peptide is a cell integrin-binding peptide that targets integrin receptors. G4RGDSP, integrin-binding peptide is coupled to alginate to increase the viability of cells in the scaffold. G4RGDSP, integrin-binding peptide can be used as an extrudable carrier for chondrocyte delivery for the study of 3D printing technology