2. Signaling Pathways
  3. GPCR/G Protein
  4. Prostaglandin Receptor
  5. EP Isoform
  6. EP Agonist

EP Agonist

EP Agonists (28):

Cat. No. Product Name Effect Purity
  • HY-19923
    Aganepag isopropyl
    		Agonist 98.61%
    Aganepag isopropyl (AGN-210961) is an EP2 agonist.
  • HY-122147
    L-644698
    		Agonist
    L-644698 is a potent and selective human recombinant prostaglandin D2 (PGD2) receptor (hDP) agonist with Ki values of 0.9, 267, 3730, 9280 nM for hDP, hEP2, hEP3, hEP4, respectively. L-644698 induces cyclic AMP production with an EC50 value of 0.5 nM.
  • HY-106054
    Nocloprost
    		Agonist
    Nocloprost, a prostaglandin E2 (PGE2) analog, is an orally active EP1- and EP3-receptor agonist. Nocloprost inhibits evoked [3H]ACh release. Nocloprost has gastroprotective and ulcer-healing properties. Nocloprost accelerates the healing of chronic gastric ulcerations and enhances mucosal growth in rats.
  • HY-150068
    EP4 receptor agonist 1
    		Agonist
    EP4 receptor agonist 1 (compound 11) is an EP4 receptor agonist with the human pEC50 value of 6.3.
  • HY-118189S
    Misoprostol acid-d5
    		Agonist
    Misoprostol acid-d5 is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].
  • HY-14898
    AGN 210676
    		Agonist
    AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.
  • HY-136696
    11-Deoxy-16,16-dimethyl-PGE2
    		Agonist
    11-Deoxy-16,16-dimethyl-PGE2, a Prostaglandin E2 analog, is a EP2 and EP3 receptors agonist. 11-Deoxy-16,16-dimethyl-PGE2 protects proximal renal tubular epithelial cells from potent nephrotoxicity-induced cell damage by exerting anti-oxidative stress.
  • HY-121091
    EP2 receptor agonist 4
    		Agonist
    EP2 receptor agonist 4 is a selective agonist for EP2 receptor with an EC50 of 43 nM.