TGF-beta/Smad Control

TGF-beta/Smad Control (1):

Cat. No.	Product Name	Effect	Purity

HY-100830A

NCB-0970	Control
NCB-0970 is the negative control of NCB-0846 (HY-100830). NCB-0846 is an orally active, selective inhibitor for Wnt, that inhibits Traf2- and Nck-interacting kinase (TNIK) with an IC₅₀ of 21 nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation.

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