2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Topoisomerase
  5. Topoisomerase Isoform
  6. Topoisomerase Agonist

Topoisomerase Agonist

Topoisomerase Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-119827
    Moflomycin
    		Agonist
    Moflomycin (F 860191) is a compound with strong anti-leukemic activity and low mutagenicity. Moflomycin has an antiproliferative effect on the leukemic cell line HL60 in vitro (IC50=2.9 nM). Moflomycin enhances topoisomerase II-induced DNA breaks and free radical production.