2. Signaling Pathways
  3. Immunology/Inflammation
  4. AP-1
  5. c-Fos Isoform
  6. c-Fos Activator

c-Fos Activator

c-Fos Activator (1):

Cat. No. Product Name Effect Purity
  • HY-113438
    15(S)-HPETE
    		Activator
    15(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A41 or reduced to 15(S)-HETE by peroxidases.2,1 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.3 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.