2. Signaling Pathways
  3. Immunology/Inflammation
  4. AP-1
  5. AP-1 Degrader

AP-1 Degrader

AP-1 Isoform Comparison

AP-1 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-162723
    FOSL1 degrader 1
    		Degrader 99.47%
    FOSL1 degrader 1 (4) is a T-5224-PROTAC, potently degrade FOSL1 (AP-1) to suppress cancer stemness gene expression in HNSCC. FOSL1 degrader 1 (4) effectively eliminate HNSCC cancer stem cells to inhibit tumor growth through degrading FOSL1. FOSL1 degrader 1 (4) displays around 30- to 100-fold increased potency over T-5224 (Pink: T-5224 (HY-12270); Black: Linker (HY-130200); Blue: Pomalidomide (HY-10984)).