2. Signaling Pathways
  3. GPCR/G Protein
  4. Arf Family GTPase
  5. Arf Family GTPase Inhibitor

Arf Family GTPase Inhibitor

Arf Family GTPase Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-111549
    Bragsin1
    		Inhibitor 99.40%
    Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity.
  • HY-151461
    CHNQD-01255
    		Inhibitor
    CHNQD-01255 is an orally active Arf-GEFs inhibitor with potent anti-hepatocellular carcinoma (HCC) efficacy.
  • HY-P10178
    Myristoylated ARF6 (2-13)
    		Inhibitor
    Myristoylated ARF6 (2-13) blocks MyD88–ARNO–ARF6–signaling axis by deactivating ARF6.