1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
  3. ASCT
  4. ASCT Agonist

ASCT Agonist

ASCT Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-I1070
    D-Isoleucine
    Agonist 99.83%
    D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value[1][2].