2. Membrane Transporter/Ion Channel
  3. ASCT
  4. D-Isoleucine

D-Isoleucine  (Synonyms: (R)-Isoleucine)

Cat. No.: HY-I1070 Purity: 99.83%
SDS
COA
Handling Instructions Technical Support

D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine.

For research use only. We do not sell to patients.

D-Isoleucine Chemical Structure

D-Isoleucine Chemical Structure

CAS No. : 319-78-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Solution
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Based on 1 publication(s) in Google Scholar

D-Isoleucine Related Antibodies

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Description

D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine[1].

Molecular Weight

131.18

Formula

C6H13NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC[C@@H](C)[C@@H](N)C(O)=O
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5.56 mg/mL (42.39 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.6234 mL 38.1170 mL 76.2340 mL
5 mM 1.5247 mL 7.6234 mL 15.2468 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.83%

SDS (393 KB)

COA (246 KB) HNMR (0 KB) RP-HPLC (241 KB) MS (81 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.6234 mL 38.1170 mL 76.2340 mL 190.5851 mL
5 mM 1.5247 mL 7.6234 mL 15.2468 mL 38.1170 mL
10 mM 0.7623 mL 3.8117 mL 7.6234 mL 19.0585 mL
15 mM 0.5082 mL 2.5411 mL 5.0823 mL 12.7057 mL
20 mM 0.3812 mL 1.9059 mL 3.8117 mL 9.5293 mL
25 mM 0.3049 mL 1.5247 mL 3.0494 mL 7.6234 mL
30 mM 0.2541 mL 1.2706 mL 2.5411 mL 6.3528 mL
40 mM 0.1906 mL 0.9529 mL 1.9059 mL 4.7646 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-Isoleucine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-Isoleucine319-78-8(R)-IsoleucineASCTAlanine Serine Cysteine TransportersInhibitorinhibitorinhibit

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