2. Signaling Pathways
  3. Autophagy
  4. Atg8/LC3
  5. Atg8/LC3 Activator

Atg8/LC3 Activator

Atg8/LC3 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-W018791
    Bifendate
    		Activator 99.91%
    Bifendate (DDB), extracted from Schisandrae chinensis, is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins (CYPs) and reverse P-gp-mediated multi-drug resistance (MDR).