2. Signaling Pathways
  3. ATP-binding Cassette (ABC) transporter
  4. ATP-binding Cassette (ABC) transporter Inhibitor

ATP-binding Cassette (ABC) transporter Inhibitor

ATP-binding Cassette (ABC) transporter Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-P10856
    CPI1
    		Inhibitor
    CPI1 is a potent and highly specific multidrug resistance protein 1 (MRP1) inhibitor. CPI1 inhibits MRP1 (Ki: 100 nM) with nanomolar potency but shows minimal inhibition of P-glycoprotein (Pgp). CPI1 and LTC4 compete to bind to the same site of MRP1, inhibiting ATP hydrolysis and substrate transport. CPI1 can be used to study drug delivery and chemotherapy resistance in cancer.