2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. ClpP
  5. ClpP Activator

ClpP Activator

ClpP Activators (4):

Cat. No. Product Name Effect Purity
  • HY-164064
    Anticancer agent 230
    		Activator 99.97%
    Anticancer agent 230 (example 65) is a caseinolytic protease P (ClpP) activator with anticancer activity. Anticancer agent 230 is able to induce the degradation of mitochondrial proteins in SUM159 and MDA-MB-231 triple-negative breast cancer cells in a time-dependent manner.
  • HY-168062
    ZYZ-17
    		Activator
    ZYZ-17 is an activator of human caseinolytic peptidase P ( hClpP), with an EC50 value of 0.24 μM. ZYZ-17 can be used in anticancer research.
  • HY-126046
    ACP1b
    		Activator
    ACP1b is an activator for ClpP protease with Kd of 3.2 μM, and exhibits antibacterial activity. ACP1b inhibits N. meningitidis and H. influenzae with MBC of 16 and 8 μg/mL.
  • HY-163319
    NCA029
    		Activator
    NCA029 is a potent and selective homo sapiens caseinolytic protease P (HsClpP) activator with an EC50 of 0.15 μM. NCA029 acts on HsClpP to activate an ATF3-dependent integrative stress response, leading to colon cancer cell death.