2. Signaling Pathways
  3. ELOVL
  4. ELOVL Inhibitor

ELOVL Inhibitor

ELOVL Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-160912
    ELOVL6-IN-5
    		Inhibitor
    ELOVL6-IN-5 (compound B) is an inhibitor of the elongase enzyme of long-chain fatty acid family 6 (ELOVL6). ELOVL6 is a rate-limiting enzyme for the elongation of saturated and monounsaturated long-chain fatty acids and is an effective target for inhibiting diabetes. ELOVL6-IN-5 reduces hepatic fatty acid levels in a mouse model of diet-induced obesity (DIO). However, ELOVL6 inhibition by ELOVL6-IN-5 did not improve insulin resistance.