ELOVL6-IN-5

Cat. No.: HY-160912 Purity: 95.12%: FAQs
Data Sheet SDS COA Handling Instructions

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ELOVL6-IN-5 (compound B) is an inhibitor of the elongase enzyme of long-chain fatty acid family 6 (ELOVL6). ELOVL6 is a rate-limiting enzyme for the elongation of saturated and monounsaturated long-chain fatty acids and is an effective target for inhibiting diabetes. ELOVL6-IN-5 reduces hepatic fatty acid levels in a mouse model of diet-induced obesity (DIO). However, ELOVL6 inhibition by ELOVL6-IN-5 did not improve insulin resistance.

For research use only. We do not sell to patients.

ELOVL6-IN-5 Chemical Structure

CAS No. : 1135000-36-0

Size	Price	Stock	Quantity
5 mg	USD 135	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 215	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 430	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 690	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 1100	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Description

Molecular Weight

439.45

Formula

C₂₀H₂₀F₃N₃O₃S

CAS No.

1135000-36-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(N1C2CCC1CC(S(=O)(C3=NC=CC=C3)=O)C2)NC4=CC=C(C(F)(F)F)C=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 95.12%

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Data Sheet (264 KB) SDS (251 KB)

COA (246 KB) HNMR (275 KB) RP-HPLC (268 KB) MS (68 KB)

Handling Instructions (2659 KB)

References

[1]. Shimamura K, et al. Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6. Eur J Pharmacol. 2010 Mar 25;630(1-3):34-41. [Content Brief]

ELOVL6-IN-5 Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ELOVL6-IN-51135000-36-0ELOVLElongation of Very Long-chain Fatty AcidsBiological phospholipid membraneconcentric phospholipid bilayer membraneanticanceranti-infectiondrug delivery systemwater-soluble drugslipophilic drugsantisense oligonucleotidescellular uptakeInhibitorinhibitorinhibit

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