2. Signaling Pathways
  3. ELOVL

ELOVL

Elongation of Very Long-chain Fatty Acids

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-145272
    ELOVL1-IN-3
    		99.81%
    ELOVL1-IN-3 (Compound 22) is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD)[1].
    ELOVL1-IN-3
  • HY-160912
    ELOVL6-IN-5
    		Inhibitor
    ELOVL6-IN-5 (compound B) is an inhibitor of the elongase enzyme of long-chain fatty acid family 6 (ELOVL6). ELOVL6 is a rate-limiting enzyme for the elongation of saturated and monounsaturated long-chain fatty acids and is an effective target for inhibiting diabetes. ELOVL6-IN-5 reduces hepatic fatty acid levels in a mouse model of diet-induced obesity (DIO). However, ELOVL6 inhibition by ELOVL6-IN-5 did not improve insulin resistance.
    ELOVL6-IN-5
Cat. No. Product Name / Synonyms Application Reactivity