2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. LDLR
  5. LDLR Inducer

LDLR Inducer

LDLR Inducer (1):

Cat. No. Product Name Effect Purity
  • HY-159595
    PCSK9-IN-29
    		Inducer
    PCSK9-IN-29 is a lipid-lowering agent. PCSK9-IN-29 can increase low-density lipoprotein receptor (LDLR) protein expression and decrease PCSK9 protein expression in hepG2 cells. PCSK9-IN-29 can reduce the levels of serum LDL-C, TC, and liver enzyme ALT in crab eating macaques fed a high-fat diet, lower body weight and fat, and increase bone mineral content. PCSK9-IN-29 can be used for research on non-alcoholic fatty liver disease and obesity.