2. Signaling Pathways
  3. GPCR/G Protein
  4. Natriuretic Peptide Receptor (NPR)
  5. Natriuretic Peptide Receptor (NPR) Antagonist

Natriuretic Peptide Receptor (NPR) Antagonist

Natriuretic Peptide Receptor (NPR) Antagonists (2):

Cat. No. Product Name Effect Purity
  • HY-P1419
    AP 811
    		Antagonist 98.07%
    AP 811 is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a Ki of 0.48 nM. AP 811 displays >20000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation.
  • HY-P2026
    A 71915
    		Antagonist 99.95%
    A 71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist (pKi= 9.18). A 71915 displaces [125I]ANP dose dependently, with a Ki of 0.65 nM. A71915( pA2= 9.48) against rat ANP-induced cGMP production in NB-OK-1 cells.