1. Signaling Pathways
  2. GPCR/G Protein
  3. Neuromedin U Receptor (NMUR)
  4. Neuromedin U Receptor (NMUR) Isoform

Neuromedin U Receptor (NMUR)

 

Neuromedin U Receptor (NMUR) Related Products (7):

Cat. No. Product Name Effect Purity
  • HY-145086
    R-PSOP
    Antagonist 99.90%
    R-PSOP is highly potent and selective nonpeptidic NMUR2 antagonist. R-PSOP binds to NMUR2 with the Kis of 52 and 32 nM for the human and rat NMUR2, respectively. R-PSOP shows moderate CNS penetration. R-PSOP can be used for the research of the eating disorders, obesity, pain, and stress-related disorders.
  • HY-P1238A
    Neuromedin U, rat TFA
    99.69%
    Neuromedin U, rat TFA is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.
  • HY-P3134A
    CPN-267 TFA
    Agonist
    CPN-267 (compound 7b) TFA is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 TFA suppresses body weight gain in mice and can be used for study of obesity.
  • HY-P3134
    CPN-267
    Inhibitor
    CPN-267 (compound 7b) is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 suppresses body weight gain in mice and can be used for study of obesity.
  • HY-P5084
    Neuromedin S (human)
    Modulator
    Neuromedin S (human) is a neuropeptide that contains 33 amino acids. Neuromedin S (human)has been identified in the brain as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1 and acts on the neuromedin U (NMU) receptor 2 (NMUR2) in the regulation of body weight homeostasis.
  • HY-P1238
    Neuromedin U, rat
    Neuromedin U, rat is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.
  • HY-124681
    NY0116
    Agonist
    NY0116 is a neuromedin U receptor 2 (NMUR2) agonist with EC50 values of 27.76 μM for hNMUR1 and 13.61 μM for hNMUR2. NY0116 decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells.