2. Signaling Pathways
  3. GPCR/G Protein
  4. Neuromedin U Receptor (NMUR)
  5. Neuromedin U Receptor (NMUR) Isoform

Neuromedin U Receptor (NMUR)

 

Neuromedin U Receptor (NMUR) Related Products (4):

Cat. No. Product Name Effect Purity
  • HY-145086
    R-PSOP
    		Antagonist 99.90%
    R-PSOP is highly potent and selective nonpeptidic NMUR2 antagonist. R-PSOP binds to NMUR2 with the Kis of 52 and 32 nM for the human and rat NMUR2, respectively. R-PSOP shows moderate CNS penetration. R-PSOP can be used for the research of the eating disorders, obesity, pain, and stress-related disorders.
  • HY-P5084
    Neuromedin S (human)
    		Modulator
    Neuromedin S (human) is a neuropeptide that contains 33 amino acids. Neuromedin S (human)has been identified in the brain as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1 and acts on the neuromedin U (NMU) receptor 2 (NMUR2) in the regulation of body weight homeostasis.
  • HY-P10473
    CPN-351
    		Antagonist
    CPN-351 (compound 9a) is a selective antagonist of hNMUR1. CPN-351 can be used in the study of inflammation and cancer.
  • HY-124681
    NY0116
    		Agonist
    NY0116 is a neuromedin U receptor 2 (NMUR2) agonist with EC50 values of 27.76 μM for hNMUR1 and 13.61 μM for hNMUR2. NY0116 decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells.