2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. p97
  5. p97 Activator

p97 Activator

p97 Activators (4):

Cat. No. Product Name Effect Purity
  • HY-168325
    UP12
    		Activator
    UP12 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 1.24 μM.
  • HY-157508
    VCP Activator 1
    		Activator 99.71%
    VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity. VCP Activator 1 binds an allosteric pocket near the C-terminus. In addition, VCP Activator 1 binding site can also be occupied by a phenylalanine residue in the VCP C-terminal tail.
  • HY-168324
    UP158
    		Activator
    UP158 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 2.57 μM.
  • HY-168323
    UP163
    		Activator
    UP163 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 9.0 μM. UP163 reduces MG-132 (HY-13259)-induced TDP-43 aggregates.